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preDQ - Update & Upgrade Update and maintenance of the preDQ - software tool for peptide binding prediction to HLA-DQ2 and HLA-DQ8

EFSA (European Food Safety Authority) · European Union · published 15 Jul 2026

preDQ is a software tool for prediction of peptides binding to HLA‐DQ2 and HLA‐DQ8 proteins, associated with susceptibility to celiac disease. preDQ was designed to evaluate the risk of novel proteins to cause celiac disease following EFSA's guidance on assessment of genetically modified plants. The predictive capability of preDQ relies on the utilization of five robust models, each producing five corresponding risk assessment outputs. These models have been developed using datasets containing both known binding and non‐binding peptides to HLA‐DQ2.5 and HLA‐DQ8.1.

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